Bacillus subtilis as a probiotic in poultry farming: relevant aspects in recent research
Keywords:
immunityAbstract
The present article is a compilation of papers that show the use of probiotics as an alternative to the use
of antibiotics as growth promoters. The benefits of Basillus subtilis had been found in a wide variety of
environments and their use as a probiotic has been extensively studied. It has been shown that B. subtilis
as a probiotic is of safe use in the feeding broiler without negative effects on the environment. Others of
the relevant characteristics of B. subtilis are their action on the stability of the intestinal microbial by
reducing the presence of E. coli, Salmonella, and Coccidia, favoring the increase of beneficial
microorganisms and improving immunity by increasing IgA and IgG. Recent research has shown that B.
subtilis contributes to the reduction of levels of ammonia in excreta, the production of antioxidant
substances and the increase of digestibility because of the equilibrium of the intestinal ecology of birds,
it has also been found that xylanases producing B. subtilis have a similar effect to antibiotics in the small
intestine. Knowing the B, subtilis as probiotic represents to improve productive parameters and sanitary
conditions of the birds.
References
GONZÁLEZ GB. 2009. Bacillus subtilis se considera seguro para pollos de engorde,
para el consumidor y para el medio ambiente. Recuperado el 05 de febrero de 2017,
de Albéitar Portal Veterinaria:
http://albeitar.portalveterinaria.com/noticia/6945/actualidad/ bacillus-subtilis-seconsidera-
seguro-para-pollos-de-engorde-para-el-consumidor-y-para-el-medioambiente.
html
BAI K, Huang Q, Zhang J, Fields G, Zhang L, Wang T. 2016. Supplemental effects of
probiotic Bacillus subtilis fmbJ on growth performance, antioxidant capacity, and meat
quality of broiler chickens. Poultry Science; 96 (1): 74-82. doi: 10.3382 / ps / pew246.
FERNÁNDEZ H, Morales M, Amela M, Salerno C, Rodríguez GH, Arenaz F, Zamponi
A. 2014. Efectos de la adición de probiótico (Bacillus subtilis) y omega 3 (Salvia
hispanica L.) sobre los parámetros sanguíneos en pollos parrilleros. Rev. Agron.
Noroeste Argent. 34 (2): 113-116. ISSN 2314-369X
FORTE C, Acuti G, Manuali E, Casagrande PP, Pavone S, Trabalza MM, Franciosini,
M. 2016. Effects of two different probiotics on microflora, morphology, and
morphometry of gut in organic laying hens. Poultry Science. 95 (11):2528-2535. DOI:
3382 / ps / pew164
GIBSON G, Roberfroid M. 1995. Dietary modulation of the human colonic microbiota:
introducing the concept of prebiotics. Journal Nutriology. 125 (6): 1401-1412.
GOROCICA RP, Chávez SR, Lascurain LR, Espinosa MB, Zenteno, GE. 1999. Óxido
nítrico, una molécula multifuncional. Rev Inst Nal Enf Resp Mex. 12 (4): 300-304.
http://www.medigraphic.com/pdfs/iner/in-1999/in994i.pdf
GRETHEL M, Pérez, M, Bocourt, R. 2008. Empleo de probióticos basado en Bacillus
sp y de sus endosporas en la producción avícola. Revista Cubana de Ciencia Agrícola
, (2): 117-122. ISSN: 0034-7485
GUEVARA J. 2011. Probióticos en nutrición animal. Sistema de Revisiones en
Investigación (SIRIVS); 1-10.
veterinaria.unmsm.edu.pe/files/Articulo_guevara_probioticos.pdf
GUO J, Dong X, Liu S, Tong J. 2016. Effects of long-term Bacillus subtilis CGMCC
921 supplementation on performance, egg quality, and fecal and cecal microbiota of
laying hens. Poultry Science. pew389. doi: 10.3382 / ps / pew389.
KUIPERS O, Konigs W, Kok, J. 2000. Lactic acid bacteria: the bug of the new
millennium. Curr Opin Microbiol; 3: 276–282. PMID: 10851157
KYUNG-WOO L, Hyun, SL, Seung J, Guangxing L, Sung-Hyen L, Erik P, Lillehoj P,
Gregory R. 2010. Effect of Bacillus-based direct-fed microbials on Eimeria maxima
infection in broiler chickens. Comparative Immunology, Microbiology and Infectious
Diseases. 33(6):105-110. DOI:10.1016 / j.cimid.2010.06.001
LEE K, Li G, Lillehoj H, Jang S, Lee S, Babu U, Siragusa G. 2011. Bacillus subtilisbased
direct-fed microbials augment macrophage function in broiler chickens.
Research in Veterinary Science.91(3):87–91
http://dx.doi.org/10.1016/j.rvsc.2011.01.018.
MANAFI M, Khalaji S, Hedayati M, Pirany N. 2016. Efficacy of Bacillus subtilis and
bacitracin methylene disalicylate on growth performance, digestibility, blood
metabolites, immunity, and intestinal microbiota after intramuscular inoculation with
Escherichia coli in broilers. Poultry Science. 2016 oct 6. doi: 10.3382 / ps / pew347.
NEWMAN R, Bryden W, Fleck, E, Ashes J, Buttermer W, Storlien L, Downing J. 2002.
Dietary n-3 and n-6 fatty acids alter avian metabolism: metabolism and abdominal fat
deposition. British Journal of Nutrition. 88:11-18. DOI:10.1079 / BJNBJN2002580
POZO D, Bitzer QO, Osuna C, García PA, Calv JM, Ortíz, GG, Guerrero JM. 1998.
Producción de óxido nítrico y su modulación en el sistema inmune y el sistema
nervioso. Arch Neurocien Mex. 3(2):84-94.
http://www.imbiomed.com.mx/1/1/articulos.php?method=showDetail&id_articulo=455
&id_seccion=21&id_ejemplar=508&id_revista=5
SALEH H. Rahimi S. Karimi TM. 2009. The effect of diet that contained fish oil on
performance, serum parameters, the immune system and the fatty acid composition of
meat in broilers. International Journal of Veterinary Research; 3(2):69-75.
https://ijvm.ut.ac.ir/pdf_20629_72a27f818938aeabcd81dc592662e03e.html
SHARMA NK, Choct M, Dunlop MW, Wu SB., Castada HZ, & Swick, R. A. 2016.
Characterisation and quantification of changes in odorants from litter headspace of
meat chickens fed diets varying in protein levels and additives. Poultry Science,
(4):851-860. DOI: 10.3382 / PS / PEW309.
VANDEPLAS S, Bodin JC. 2012. Acción de una xilanasa producida por Basilus subtilis.
Efectos sobre la flora intestinal y el estado sanitario de las aves. Selecciones Avícolas,
noviembre. Noviembre 2012: 19-22. ISSN 0210-0541
ZHANG ZF, Cho JH, Kim I. 2013. Effects of Bacillus subtilis UBT-MO2 on growth
performance, immune organ relative weight, fecal gas concentration and intestinal
microbial shedding in broiler chickens. Livest. Sci. 155:343 – 347. DOI: 10.1016 /
j.livsci.2013.05.021.
