Efeito do coumestrol sobre o epidídimo dos cães adultos
Palavras-chave:
epidídimo, espermatozóides, estrogénios, fitoestrogénicos, testículos, cão, controlo reprodutivoResumo
A preocupação do excesso de população canina está relacionada com zoonoses como a raiva, que é
responsável por 99% dos casos de raiva humana, causando a morte de aproximadamente 59.000 pessoas
por ano. A esterilização cirúrgica é um método de controlo eficaz, dispendioso e invasivo com impacto
limitado. Os efeitos dos fitoestrogénios na actividade reprodutiva têm sido geralmente estudados nas
fêmeas, e um número limitado nos machos. Portanto, o objectivo deste estudo era determinar o efeito da
administração subcutânea de coumestrol na actividade gonadal em cães adultos como uma alternativa
para o controlo reprodutivo. Foram determinados parâmetros básicos de avaliação seminal, estrutura
epididimal por ultra-sonografia, características histológicas, bem como a presença de coumestrol por
fluorescência e níveis séricos de testosterona e estrogénio. A administração de coumestrol durante cinco
semanas reduziu a produção de esperma, e mostrou alterações na equodensidade epidídima e
celularidade, associadas às concentrações de estradiol e testosterona no soro. Por conseguinte, concluise que o coumestrol administrado subcutaneamente tem um efeito estrogénico que pode ser utilizado como
método não invasivo para ajudar a controlar a fertilidade em cães adultos.
http://dx.doi.org/10.21929/abavet2022.15
https://www.youtube.com/watch?v=6d4WqxZqAqo
e2022-17
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