Performance, intestinal integrity and immune response in broilers fed diets supplemented with L- glutamine

Authors

Keywords:

AminoGut, Glutamine, Glutamic Acid, performance, intestinal villi, immune response

Abstract

In two experiments the addition of AminoGut (AG) was evaluated. In Experiment 1, 300 Ross 308 broilers were used in 5 treatments with 3 repetitions of 20 broilers each. In Experiment 2, 640 broilers were used in 4 treatments with 5 repetitions of 32 broilers each. Exp. 1 treatments: T1.- Control diet sorghum + soybean meal, T2.- As 1 + 700 ppm of the mixture of AG/ ton, T3.- As 1 + 1400 ppm of AG/ ton, T4.- As 1 + 2100 ppm of AG/ ton, T5.- As 1 + 2800 ppm of AG/ ton. In Exp. 2, treatment 5 was eliminated. In Experiment 1, there was an effect (P<0.05) on performance and carcass weight, with 700 ppm of AG. In Experiment 2, the height of intestinal villi and late hypersensitivity (P<0.05) improved with 700 ppm of AG, as well as carcass yield at 42 days. It can be concluded that the addition of 700 ppm of AminoGut in diets in broilers from 1 to 21 days of age, increased the performance, villus length, carcass yield and immune response.

http://dx.doi.org/10.21929/abavet2024.3       

e2022-37

https://www.youtube.com/watch?v=Rn-sSFpgaYA

 

References

BAREKATAIN R, Chrystal PV, Howart GSW, McLaughlan CJ, Gilani S, Nattrass GS. 2019. Performance, intestinal permeability, and gene expression of selected tight junction proteins in broiler chickens fed reduced protein diets supplemented with arginine, glutamine, and glycine subjected to a leaky gut model. Poultry Science. 98(12):6761-6771. ISSN 0032-5791. https://doi.org/10.3382/ps/pez393

BARTELL SM, Batal A B. 2007. The effect of supplemental glutamine on growth performance, development of the gastrointestinal tract, and humoral immune response of broilers. Poultry Science 86(9):1940–1947. ISSN 0032-5791.

https://doi.org/10.1093/ps/86.9.1940

BORTOLUZZI C, Rochell SJ, Applegate TJ. 2018. Threonine, arginine, and glutamine: Influences on intestinal physiology, immunology, and microbiology in broilers. Poultry Science. 97(3):937-945. ISSN 0032-5791. https://doi.org/10.3382/ps/pex394

CUCA GM, Ávila GE, Pro MA. 2009. Alimentación de las aves. Edo. México, México: Universidad Autónoma de Chapingo. ISBN: 978-607-12-0038-9.

ESTRADA FE, Peralta ZL, Rivas MP. 1982. Manual de técnicas Histológicas. AGT Editor, Sa, México. ISBN: 9789684630109.JOHN D, Christopher L. 2019. Bancroft`s Theory and Practice of Histological Techniques. United Kingdom: Elsevier. ISBN: 9780702068874. https://doi.org/10.1016/B978-0-7020-6864-5.00010-4

GÓMEZ VG, López CC, Maldonado BC, Avila GE. 2010. El sistema inmune digestivo de las aves. Investigación y Ciencia. 18(48):9-16.

https://biblat.unam.mx/hevila/InvestigacionycienciaUniversidadautonomadeaguascalientes/2010/vol18/no48/2.pdf

HU H, Bai X, Wen A, Shah AA, Dai S, Ren Q, Wang S, He S, Wang L. 2016. Assessment of interaction between glutamine and glucose on meat quality, AMPK, and glutamine concentration in pectoralis major meat of broilers under acute heat stress. Journal Applied Poultry Research. 25(3):370-378. ISSN 1056-6171.

https://doi.org/10.3382/japr/pfw021

INEGI (Instituto Nacional de Estadística y Geografía). 2017. Anuario estadístico y geográfico de la Ciudad de México. México.

https://www.inegi.org.mx/app/biblioteca/ficha.html?upc=702825094683

JARRED HO, Ramesh KS. 2019. Effects of glutamine supplementation on broiler performance and intestinal immune parameters during an experimental coccidiosis infection. Journal Applied Poultry Research. 28(4):1279-1287. ISSN 1056-6171.

https://doi.org/10.3382/japr/pfz095

KRISELDI R, Tillman PB, Jiang Z, Dozier WA. 2017. Effects of glycine and glutamine supplementation to reduces crude protein diets on growth performance and carcass characteristics of male broilers during a 41-day production period. Journal Applied Poultry Research. 26(4):558-572. ISSN 1056-6171. https://doi.org/10.3382/japr/pfx030

LEESON S, Summers JD. 2005. Comercial poultry nutrition. 3ra ed. Guelph, Ontario Canadá: University Books. ISBN: 190476178X.

LIU Z, Wu Q, Jiao C, Cheng B, Zhu D, Ma Y, Li Y, Li W. 2020. Effects of glutamineon the mucosal structure and immune cells in the intestines of broiler chickens challenged with Salmonella enteritidis. Brazilian Journal of Poultry Science. 22 (3):1-10. ISSN 1806-9061. https://doi.org/10.1590/1806-9061-2020-1270

MIGUEL IJ, Cortes CA, Ávila GE. 2009. Evaluación de la mezcla de diferentes niveles de glutamina en dietas sorgo- soya para pollos de engorda. Tesis de licenciatura, FMVZ-UNAM, México D, F.

https://ru.dgb.unam.mx/handle/DGB_UNAM/TES01000639580

MORALES LB. 2013. El uso de ácidos orgánicos en dietas para gallina, efecto en el pH intestinal, rendimiento productivo, tiempo de tránsito e integridad intestinal. (Tesis de maestría). México (D.F.) UNAM.

https://ru.dgb.unam.mx/handle/DGB_UNAM/TES01000689703

NOM-033-SAG/ZOO-2014. Norma Oficial Mexicana. Sacrificio humanitario de las aves. https://www.gob.mx/profepa/documentos/norma-oficial-mexicana-nom-033-sag-zoo-2014-metodos-para-dar-muerte-a-los-animales-domesticos-y-silvestres

OLUBODUN JO, Zukkifli I, Farjam AS, Hair-Bejo M, Kasim A. 2015. Glutamine and glutamic acid supplementation enhances performance of broiler chickens under the hot and humid tropical condition. Italian Journal Animal Science. 14:25-29. ISSN 1828-051X. https://doi.org/10.4081/ijas.2015.3263

PELICIA VCI, Stradiotti AC, Araujo PC de, Maruno MK, Carvalho FB de, Pezzato AC, Sartori JR. 2013. Phytogenic additives and glutamine plus glutamic acid in broiler diets. Brazilian Journal of Poultry Science. 15 (4):295-300. https://doi.org/10.1590/S1516-635X2013000400002

QUINTANA JA. 2011. Avitecnia. Manejo de las Aves Domésticas más comunes. 4ª ed. México. Trillas. ISBN: 6071708117.

SHAKERI M, Zulkifli I, Solieimani AF, O´Reilly EL, Eckersall PD, Anna AA, Kumari S, AbdullahFFJ. 2014. Response to dietary supplementation of L-glutamine and L-glutamate in broilerchickens reared at different stocking densities under hot, humid tropical conditions. Poultry Science. 93(11):2700-2708. https://doi.org/10.3382/ps.2014-03910

WU QJ, Liu N, Wu XH, Wang GY, Lin L. 2018. Glutamine alleviates heat stress-induced impairment of intestinal morphology, intestinal inflamatory response, and barrier integrity in broilers. Poultry Science. 97(8):2675-2683. https://doi.org/10.3382/ps/pey123

WU Q, Liu Z, Li S, Jiao C, Wang Y, Wang Y. 2019. Effects of glutamine on digestive function and redox regulation in the intestine of broiler chickens challenged with Salmonella enteritidis. Brazilian Journal of Poultry Science. 21 (4):1-10.

https://doi.org/10.1590/1806-9061-2019-1123

WU QJ, Liu ZH, Jiao C, Cheng BY, Li SW, Ma Y, Wang YQ, Wang Y. 2021. Effects of glutamine on lymphocyte proliferation and intestinal mucosal immune response in heat-stressed broilers. Brazilian Journal of Poultry Science. 23 (4): 1-10.

https://doi.org/10.1590/1806-9061-2019-1207

XI B, Sifa D, Jiaqi L, Shuangshuang X, Aiyou W, Hong H. 2019. Glutamine improves the growth performance, serum biochemical profile and antioxidant status in broilers under médium-term chronic heat stress. Journal Applied Poultry Research. 23(4):1248-1254. ISSN 1056-6171. https://doi.org/10.3382/japr/pfz091

XUE GD, Barekatain R, Wu SB, Choct M, Swick RA. 2018. Dietary L-glutamine supplementation improves growth performance, gut morphology, and serum biochemical índices of broiler chickens during necrotic enteritis challenge. Poultry Science. 97(4):1334-1341. ISSN 0032-5791. https://doi.org/10.3382/ps/pex444

ZULKIFLI I, Shakeri M, Soleimani AF. 2016. Dietary supplementation of L-glutamine and L-glutamate in broiler chicks subjected to delayed placement. Poultry Science. 95(12):2757-2763. ISSN 0032-5. https://doi.org/10.3382/ps/pew267

Published

2024-05-05

Issue

Section

Original Articles