In vitro Antiprotozoal activity of four medicinal plants from Mexico against Tritrichomonas foetus
Keywords:
activity anti-T. foetus, Tritrichomonas foetus, bovine trichomonosis, Etnomedicinal plants, Tagetes nelsoniiAbstract
Tritrichomonas foetus is a flagellated protist parasite of the bovine reproductive system; it is the agent responsible for bovine trichomoniasis. Worldwide, cases of bovine trichomoniasis have increased, and in developing countries like Mexico there are few alternatives for its control. Therefore, the use of natural products could serve as a complementary therapy for its treatment. This work analyzes the antiprotozoal effect of hexanic and methanolic extracts from Cordia dodecandra, Gaultheria odorata, Tagetes nelsonii and Talisia oliviformis, plants used in ethnomedicine in Mexico, against T. foetus. Extracts were obtained through sonication-assisted maceration, and antiprotozoal activity was as assessed at concentrations ≤ 500 μg/mL using a manual hemocytometer. In addition, a semiquantitative phytochemical was conducted for each extract. The anti-trichomonas activity varied among the extracts from the same plant, with the hexane extract of T. nelsonii showing the most potent activity, with a mean inhibitory concentration (IC50) value of 275.75 μg/mL. The results of this study represent the first report on the use of medicinal from Mexican ethnic cultures in the investigation of natural products for treatmenting bovine trichomoniasis.
http://dx.doi.org/10.21929/abavet2025.8
e2024-37
https://www.youtube.com/watch?v=M-EZjP2CXzo
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