Synchronization of estrus and ovulation in bovine females. Endocrine bases and treatments used
Keywords:
oestrous cycle, waves of follicular growth, synchronization of estrus and ovulation, beef cowsAbstract
In Mexico, reproductive performance in beef cows is low and the use of synchronization of estrus and ovulation may help to improve it, thus the objective of this review was to describe the endocrine regulation the oestrus cycle and follicular dynamics in cattle, highlighting how these processes can be manipulated by using exogenous hormones. Moreover, we also present some data of pregnancy per artificial insemination (P/AI) with the different protocols of synchronization of estrus and ovulation reported in the literature. Reviews and original articles on the estrus cycle and follicular dynamics in cattle were compiled and PRSE data were obtained from papers published from 2000 to 2023. The range of P/AI was from of 23 to 76%, however despite this wide range, in treatments based on estradiol and GnRH around of 50% of the data of P/AI are between 45 and 55%. In progestin-based protocols, 50% of the P/AI observations were between 55 and 65%. Currently, there are three main protocols for synchronizing oestrus and ovulation that can be used, agree with the revised literature herein, to obtain P/AI between 45 and 65% in most cases with these protocols.
http://dx.doi.org/10.21929/abavet2023.16
e2022-11
https://www.youtube.com/watch?v=k2kox38NV-k
References
ABEL, JM, Bishop BE, Thomas JM, Ellersieck MR, Poock SE, Smith MP, Patterson DJ. 2017. Comparing strategies to synchronize estrus before fixed-time artificial insemination in primiparous 2-year-old beef cows. Theriogenology. 87:306-315. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2016.09.010
ABREU FM, Da Silva MAC, Cruppe LH, Mussard ML, Bridges GA, Harstine BR. 2018. Role of progesterone concentrations during early follicular development in beef cattle: I. Characteristics of LH secretion and oocyte quality. Animal Reproduction Science. 196:59-68. ISSN:0378-4320. https://doi.org/10.1016/j.anireprosci.2018.06.020
ADAMS GP, Matteri RL, Ginther OJ. 1992. Effect of progesterone on ovarian follicles, emergence of follicular waves and circulating follicle-stimulating hormone in heifers. Journal of Reproduction and Fertility. 96(2):627-40. ISSN: 2228-5482. https://pubmed.ncbi.nlm.nih.gov/1339842/
AERTS JMJ, Bols PEJ. 2010. Ovarian follicular dynamics. A review with emphasis of the bovine species. Part II: antral development, exogenous influence and future prospects. Reproduction in Domestic Animals. 45:180–7. ISSN: 1439-0531. https://doi.org/10.1111/j.1439-0531.2008.01298.x
ALVES RLOR, Silva MA, Consentini CEC, E Silva LO, Folchini NP, Oliva AL, Prata AB, Gonçalves JRS, Wiltbank MC, Sartori R. 2021. Hormonal combinations aiming to improve reproductive outcomes of Bos indicus cows submitted to estradiol/progesterone-based timed AI protocols. Theriogenology. 15;169:89-99. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2021.04.007
ALVAREZ RH, Pugliesi G, Nogueira-Natal FL, Rocha CC, Ataide-Júnior GA, Ferreira-Melo AJ. 2018. Reproductive performance of Bos indicus beef cows treated with different doses of equine chorionic gonadotropin at the end of a progesterone-estrogen based protocol for fixed-time artificial insemination. Theriogenology. 118:150-156. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2018.06.003
ARAGUNDE VIEYTES R, Viñoles Gil C, Gastal GDA, Cavestany D. 2023. Equine chorionic gonadotropin administered on day 5 of a 7-days fixed-time artificial insemination program improves ovulation synchrony and corpus luteum function in anestrous beef cows. Theriogenology. 195:62-68. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2022.10.016
BADER JF, Kojima FN, Schafer DJ, Stegner JE, Ellersieck MR, Smith MF, Patterson DJ. 2005. A comparison of progestin-based protocols to synchronize ovulation and facilitate fixed-time artificial insemination in postpartum beef cows. Journal of Animal Science. 83:136-143. ISSN: 1525-3163. https://doi.org/10.2527/2005.831136x
BARBOSA IP, Cestaro JP, Silva SA, Noleto GS, Gonçalves RL, Silva GM, Paes FH, Gasperin BG, Rovani MT, Pfeifer LFM. 2022. GnRH34: An alternative for increasing pregnancy in timed AI beef cows. Theriogenology. 179:1-6. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2021.11.014
BARUSELLI P, Gimenes L, Sales JN, 2007. Fisiologia reprodutiva de fêmeas taurinas e zebuínas. Revista Brasileira de Reprodução Animal. Belo Horizonte. 31(2):205-211. ISSN: 1809-3000. Disponible en https://www.academia.edu/18955421/
BARUSELLI PS, Ferreira RM, Sa MF, Bo GA. 2018. Review: Using artificial insemination v. natural service in beef herds. Animal. 12:S45-S52. ISSN: 1751-732X. https://doi.org/10.1017/S175173111800054X
BEG MA, Ginther OJ, 2006. Follicle selection in cattle and horses: role of intrafollicular factors. Reproduction. 132:365-377. ISSN: 1741-7899.
https://doi.org/10.1530/rep.1.01233
BISHOP BE, Thomas JM, Abel JM Poock SE, Ellersieck MR, Smith MF. 2017. Split-time artificial insemination in beef cattle: III. Cmparing fixed-time artificial insemination to Split-time artificial insemination with delayed administration of GnRH in postpartum cows. Theriogenology. 99:48-52. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2017.04.046
BÓ GA, Adams GP, Pierson RA, Tribulo HE, Caccia M, Mapletoft RJ. 1994. Follicular wave dynamics after estradiol-17β treatment of heifers with or without a progestogen implant. Theriogenology. 41:1555-1569. ISSN: 0093-691X.
https://doi.org/10.1016/0093-691X(94)90821-Y
BÓ GA, Baruselli PS, Martinez MF. 2003. Pattern and manipulation of follicular development in Bos indicus cattle. Animal Reproduction Science. 78:307-326. ISSN:0378-4320. https://doi.org/10.1016/s0378-4320(03)00097-6
BÓ GA, Baruselli, PS. 2014. Synchronization of ovulation and fixed-time artificial insemination in beef cattle. Animal. 8:144-150. ISSN: 1751-732X.
https://doi.org/10.1017/S1751731114000822
BÓ GA, De La Mata JJ, Baruselli PS, Menchaca A. 2016. Alternative programs for synchronizing and resynchronizing ovulation in beef cattle. Theriogenology. 86:388-396. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2016.04.053
BONACKER RC, Stoecklein KS, Locke JWC, Ketchum JN, Knickmeyer ER, Spinka CM, Poock SE, Thomas JM. 2020. Treatment with prostaglandin F2α and an intravaginal progesterone insert promotes follicular maturity in advance of gonadotropin-releasing hormone among postpartum beef cows. Theriogenology. 157:350-359. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2020.08.018
BRIDGES GA, Lake SL, Kruse SG, Bird SL, Funnell BJ, Arias R. 2014. Comparison of three DIP-based fixed-time AI protocols in beef heifers. Journal of Animal Science. 93:3127-313. ISSN: 1525-3163. https://doi.org/10.2527/jas.2013-7404
BURNS MG, Buttrey BS, Dobbins C.A, Martel CA, Olson KC, Lamb GC. 2008. Evaluation of human chorionic gonadotropin as a replacement for gonadotropin-releasing hormone in ovulation–synchronization protocols before fixed timed artificial insemination in beef cattle. Journal of Animal Science. 86:2539-2548. ISSN: 1525-3163. https://doi.org/10.2527/jas.2008-1122
BUSCH DC, Schafer DJ, Wilson DJ, Mallory DA, Leitman NR, Haden JK. 2008. Timing of artificial insemination in postpartum beef cows following administration of the CO.synch+cotrolled internal drug-release protocol. Journal of Animal Science. 86:1519-1525. ISSN: 1525-3163. https://doi.org/10.2527/jas.2008-0925
BUSCH DC, Wilson DJ, Schafer DJ, Leitman NR, Haden JK, Ellersieck. 2007. Comparison of progestin-based estrus sinchronization protocols before fixed-time artificial insemination on pregnancy rate in beef heifers. Journal of Animal Science. 85:1933-1939. ISSN: 1525-3163. https://doi.org/10.2527/jas.2006-845
CAMPOS JT, Marinho LS, Lunardelli PA, Morotti F, Seneda MM. 2013. Resynchronization of estrous cycle with eCG and temporary calf removal in lactating Bos indicus cows. Theriogenology. 80:619-23. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2013.05.029
CEDEÑO AV, Cuervo R, Tríbulo A, Tríbulo R, Andrada S, Mapletoft R, Menchaca A, Bó GA. 2021. Effect of expression of estrus and treatment with GnRH on pregnancies per AI in beef cattle synchronized with an estradiol/progesterone-based protocol. Theriogenology. 161:294-300. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2020.12.014
COLAZO MG, Mapletoft RJ. 2014. A review of current timed-AI (TAI) programs for beef and dairy cattle. Canadian Veterinary Journal. 55:772-780. ISSN: 85286. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095965/
COLAZO MG, Kastelic JP, Mapletoft RJ. 2003. Effects of estradiol Cypionate (ECP) on ovarian follicular dynamics, synchrony of ovulation, and fertility in DIP-based, fixed-time AI programs in beef heifers. Theriogenology. 60:855-865. ISSN: 0093-691X. https://doi.org/10.1016/s0093-691x(03)00091-8
COLAZO MG, Whittaker P, Macmillan K, Bignell D, Boender G, De Carvalho-Guimaraes, R. 2018. Evaluation of a modified GnRH-based timed-AI protocol associated with estrus detection in beef heifers inseminated with sex-selected or conventional semen. Theriogenology. 118:90-95. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2018.05.037
COOKE RF, Peres RFG, Cipriano RS, Guarnieri-Filho TA, Marques RS, Rodrigues MC. 2016. Impacts of meloxicam prior to temporary calf weaning on physiological and reproductive responses of Bos indicus beef cows. Journal of Animal Science. 94:406–411. ISSN: 1525-3163. https://doi.org/10.2527/jas2015-9222
CREPALDI GA, Sales JNS, Girotto RW, Carvalho JGS, Baruselli PS. 2019. Effect of induction of ovulation with estradiol benzoate at P4 device removal on ovulation rate and fertility in Bos indicus cows submitted to a TAI protocol. Animal Reproduction Science. 209:106141. ISSN: 1873-2232. https://doi.org/10.1016/j.anireprosci.2019.106141
CROWE MA. 2008. Resumption of ovarian cyclicity in post-partum beef and dairy cows. Reproduction in Domestic Animals Suppl. 5:20-8. ISSN: 0936-6768. https://doi.org/10.1017/S1751731114000251
CRUPPE LH, Day ML, Abreu FM, Kruse S, Lake SL, Biehl MV. 2014. The requirement of GnRH at the beginning of the five-day Co-Synch+controlled internal drug release protocol in beef heifers. Journal of Animal Science. 92:4198-4203. ISSN: 1525-3163. https://doi.org/10.2527/jas.2014-7772
DAHLEN CR, Bird SL, Martel CA, Olson KC, Stevenson JS, Lamb GC. 2010. Administration of human chorionic gonadotropin 7 days after fixed-time artificial insemination of suckled beef cows. Journal of Animal Science. 88:2337-2345. ISSN: 1525-3163. https://doi.org/10.2527/jas.2009-2596
DAY ML. 2015. State of the art of GnRH - based timed AI in beef cattle. Animal Reproduction. 12:473-478. ISSN 0378-4320. https://www.animal-reproduction.org/journal/animreprod/article/5b5a6032f7783717068b4611
DE GRAAFF W, Grimard B. 2018. Progesterone-releasing devices for cattle estrus induction and synchronization: Device optimization to anticipate shorter treatment durations and new device developments. Theriogenology. 112:34-43. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2017.09.025
DELGADO PAM, Cuéllar NR, Sánchez CMG, Rojas ECC. 2011. Dinámica folicular en la vida reproductiva de la hembra bovina. Veterinária e Zootecnia. 5:88-99. ISSN: 2178-3764. http://vetzootec.ucaldas.edu.co/downloads/v5n2a08.pdf
DINIZ JHW, Peres RFG, Teixeira ACB, Riveros JAN, Noronha IM, Martins CFG, Oliveira CS, Pohler KG, Pugliesi G, Oliveira LZ. 2021. Administration of PGF2α at the moment of timed-AI using sex-sorted or conventional semen in suckled nelore cows with different intensity of estrus behavior. Theriogenology. 15;174:169-175. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2021.08.023
DRIANCOURT MA. 2001. Regulation of ovarian follicular dynamics in farm animals. Implications for manipulation of reproduction. Theriogenology. 55:1211-1239. ISSN: 0093-691X. https://doi.org/10.1016/s0093-691x(01)00479-4
EBORN DR, Grieger, DM. 2013. Timed insemination of beef heifers using the 7-11 Synch protocol. Journal of Animal Science. 91:666-672. ISSN: 1525-3163.
https://doi.org/10.2527/jas.2011-4951
ECHTERNKAMP SE, Thallman RM. 2011. Factors affecting pregnancy rate to estrus synchronization and fixed-time artificial insemination in beef Cattle. Journal of Animal Science. 89:3060-3068. ISSN: 1525-3163. https://doi.org/10.2527/jas.2010-3549
ESTERMAN RD, Alava EN, Austin BR, Hersom MJ. 2016. Select Synch and Co-Synch protocols using a DIP yield similar pregnancy rate after a fixed-time insemination in suckled Bos indicus x Bos taurus cows. Theriogenology. 85:870-876. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2015.10.035
FERREIRA RM, Conti TL, Goncalves RL, Souto LA, Sales JNS, Sa MF. 2018. Synchronization treatments previous to natural breeding anticipate and improve the pregnancy rate of postpartum primiparous beef cows. Theriogenology. 114:206-211. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2017.11.022
FIGUEIREDO RA, Barros CM, Pinheiro OL, Soler JMP. 1997. Ovarian follicular dynamics in nelore breed (Bos indicus) cattle. Theriogenology. 47:1489-1505. ISSN: 0093-691X. https://doi.org/10.1016/S0093-691X(97)00156-8
FORDE N, Beltman ME, Lonergan P, Diskin M, Roche JF, Crowe MA. 2011. Oestrous cycles in Bos taurus cattle. Animal Reproduction Science. 124:163-169. ISSN:0378-4320. https://doi.org/10.1016/j.anireprosci.2010.08.025
FORTUNE JE, Sirois J, Turzillo AM, Lavoir M. 1991. Follicle selection in domestic ruminants. Journal Reproduction and Fertility Supplement. 43:187-98. SSN:04493087. https://www.biosciproceedings.org/bp/0002/pdf/bp0002rdr15.pdf
FORTUNE JE, Rivera GM, Evans ACO, Turzillo AM. 2001. Differentiation of dominant versus subordinate follicles in cattle. Biology of Reproduction. 65:648-654. ISSN: 00063363. https://doi.org/10.1095/biolreprod65.3.648
GARVERICK HA, Smith MF. 1993. Female reproductive physiology and endocrinology of cattle. Veterinary Clinics of North America: Food Animal Practice. 9(2):223-247. ISSN: 07490720. https://doi.org/10.1016/s0749-0720(15)30643-5
GEARY TW, Whittier JC, Hallford DM, MacNeil MD. 2001. Calf removal improves conception rates to the Ovsynch and Co-Synch protocols. Journal of Animal Science. 79:1-4. ISSN: 1525-3163. https://doi.org/10.2527/2001.7911
GILES RL, Ahola JK, Whittier JC, French JT, Repenning PE, Kruse SG. 2013. Administration of a GnRH analog on day 9 of a 14-day controlled internal drug release insert with timed artificial insemination in lactating beef cows. Journal of Animal Science. 91:1866-1873. ISSN: 1525-3163. https://doi.org/10.2527/jas.2012-5497
GINTHER OJ, Kastelic JP, Knopf L. 1989. Intraovarian relationships among dominant and subordinate follicles and the corpus luteum in heifers. Theriogenology. 32:787-795. ISSN: 0093-691X. https://doi.org/10.1016/0093-691x(89)90467-6
GINTHER OJ. 2016. The theory of follicle selection in cattle. Domestic Animal Endocrinology. 57: 85-99. ISSN: 18790054.
https://doi.org/10.1016/j.domaniend.2016.06.002
GUTIÉRREZ GC. 2018. Simposio Vaca-Cría. Manejos Ganaderos en el sistema Vaca Cría En: 54 Reunión Nacional de Investigación Pecuaria. Año 4. Vol. 1 Núm.1. Nayarit México.
HALL JB, Kasimanickam RK, Glaze Jr JB, Roberts-lew MC. 2017. Impact of delayed insemination on pregnancy rates to gender selected semen in a fixed-timeAI system. Theriogenology. 102:154-161 ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2017.07.014
HELGUERA IL, Whittaker P, Behrouzi A, Mapletoft RJ, Colazo MG. 2018. Effect of initial GnRH and time of insemination on reproductive performance in cyclic and acyclic beef heifers subjected to a 5-d Co-synch plus progesterone protocol. Theriogenology. 106:39-45. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2017.10.001
HILL SL, Grieger DM, Olson KC, Jaeger JR, Dahlen CR, Bridges GA. 2016a. Using estrus detection patches to optimally time insemination improved pregnancy risk in suckled beef cows enrolled in a fixed-time artificial insemination program. Journal of Animal Science. 94(9):3703-3710. ISSN: 1525-3163. https://doi.org/10.2527/jas.2016-0469
HILL SL, Grieger DM, Olson KC, Jaeger JR, Dahlen CR, Crosswhite MR. 2016b. Gonadotropin-releasing hormone increased pregnancy risk in suckled beef cows not detected in estrus and subjected to a Split-time artificial insemination program. Journal of Animal Science. 94:3722-3728. ISSN: 1525-3163. https://doi.org/10.2527/jas.2016-0582
HILL SL, Perry GA, Mercadante VRG, Lamb GC, Jaeger JR, Olson KC., 2014. Altered progesterone concentrations by hormonal manipulations before a fixed-time artificial insemination CO-Synch+DIP program in suckled beef cows. Theriogenology. 82:104-113. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2014.03.008
KASIMANICKAM R, Asay M, Firth P, Whittier WD, Hall JB. 2012. Artificial insemination at 56 h after intravaginal progesterone device removal improved AI pregnancy rate in beef heifers synchronized with five-day CO-Synch+controlled internal drug release (DIP) protocol. Theriogenology. 77:1624-1631. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2011.12.007
KASIMANICKAM R, Collins JC, Wuenschell J, Currin JC, Hall JB, Whittier DW. 2006. Effect of timing of prostaglandin administration, controlled internal drug release removal and gonadotropin releasing hormone administration on pregnancy rate in fixed-time AI protocols in crossbred Angus cows. Theriogenology. 66:166-172. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2005.10.019
KASIMANICKAM R, Day ML, Rudolph JS, Hall JB, Whittier WD. 2009. Two doses of prostaglandin improve pregnancy rates to timed-AI in a 5-day progesterone-based synchronization protocol in beef cows. Theriogenology. 71:762-767. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2008.09.049
KASIMANICKAM R, Hall JB, Currin JF, Inman B, Rudolph JS, Whittier WD. 2010. Pregnancy rates in angus cross beef cows bred at observed oestrus with or without second GnRH administration in fixed-timeprogesterone-supplemented ovsynch and co-synch protocols. Reproduction in Domestic Animals. 45:487-492. ISSN: 1439-0531. https://doi.org/10.1111/j.1439-0531.2008.01269.x
KASIMANICKAM RK, Firth P, Schuenemann GM, Whtlock BK, Gay JM, Moore DA. 2014. Effect of the first GnRH and two doses of PGF2α in a 5-day progesterone-based CO-Synch protocol on heifer pregnancy. Theriogenology. 81:797-804. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2013.12.023
KASIMANICKAM RK, Hall JB, Whittier WD. 2016. Fertility of Angus cross beef heifers after GnRH treatment on day 23 and timing of insemination in 14-day DIP protocol. Journal of Animal Science. 52(1):122-129. ISSN: 1525-3163. https://doi.org/10.1111/rda.12866
KENEALY BP, Terasawa E. 2012. Rapid direct action of estradiol in GnRH neurons: findings and implications. Front Endocrinol (Lausanne). 3(2):106.
https://doi.org/10.3389/fendo.2011.00106
KETCHUM JN, Bonacker RC, Andersen CM, Smith EG, Stoecklein KS, Spinka CM, Thomas JM. 2021. Evaluation of later timepoints for split-time artificial insemination when using sex-sorted semen among beef heifers following the 14-d CIDR®-PG protocol. Animal Reproduction Science. 224:106649. ISSN: 1873-2232J.
https://doi.org/10.1016/j.anireprosci.2020.106649
KNICKMEYER ER, Thomas JM, Locke JWC, Bonacker RC, Ellersieck MR, Poock SE. 2019. Evaluation of split-time artificial insemination following administration of a long or short-term progestin-based estrus synchronization protocol in beef heifers. Theriogenology. 133:179-186. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2019.04.011
LAMB GC, Stevenson JS, Kesler DJ, Garverick HA, Brown DR, Salfen BE. 2001. Inclusion of an intravaginal progesterone Insert plus GnRH and prostaglandin F2α for ovulation control in postpartum suckled beef cows. Journal of Animal Science. 79:2253-2259. ISSN: 1525-3163. https:/doi.org/10.2527/2001.7992253x
LAMB GC, Larson JE, Geary TW, Stevenson JS, Johnson SK, Day ML. 2006. Synchronization of estrus and artificial insemination in replacement beef heifers using gonadotropin-releasing hormone, prostaglandin F2α and progesterone. Journal of Animal Science. 84:3000-3009. ISSN: 1525-3163. https://doi.org/10.2527/jas.2006-220
LAMB GC, Mercadante VRG. 2016. Synchronization and Artificial Insemination Strategies in Beef Cattle. Veterinary Clinics of North America: Food Animal Practice. 32:335-347. ISSN: 07490720. https://doi.org/10.1016/j.cvfa.2016.01.006
LAMB GC, Dahlen CR, Larson JE, Marquezini G, Stevenson JS. 2010. Control of the estrous cycle to improve fertility for fixed-time artificial insemination in beef cattle: a review. Journal of Animal Science. 88:E181-192. https://doi.org/10.2527/jas.2009-2349
LARSON JE, Lamb GC, Stevenson JS, Johnson SK, Day ML, Geary TW. 2006. Synchronization of estrus in suckled beef cows for detected estrus and artificial insemination and timed artificial insemination using gonadotropin-releasing hormone, prostaglandin F2α, and progesterone. Journal of Animal Science. 84:332-342. ISSN: 1525-3163. https://doi.org/10.2527/2006.842332x
LASSALA A, Hernández-Cerón J, Pedernera M, González-Padilla E, Gutierrez CG. 2020. Cow-calf management practices in Mexico: Reproduction and breeding. Veterinaria Mexico OA. 7(1). ISSN: 2448-6760. https://doi.org/10.22201/fmvz.24486760e.2020.1.839
MACMILLAN K, Gobikrushanth M, Sanz A, Bignell D, Boender G, Macrae L. 2020. Comparison of the effects of two shortened timed-AI protocols on pregnancy per AI in beef cattle. Theriogenology. 15:142:85-91. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2019.09.038
MALIK A, Wahid H, Rosnina Y, Kasim A, Sabri M. 2012. Effects of timed artificial insemination following estrus synchronization in postpartum beef cattle. Open Veterinary Journal. 2(1):1–5. ISSN:2218-6050.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655776/
MALLORY DA, Nash JM, Ellersieck MR, Smith MF, Patterson DJ. 2011. Comparison of long-term progestine-based protocols to synchronize estrus before fixed-time artificial insemination in beef heifers. Journal of Animal Science. 89:1358-1365. ISSN: 1525-3163. https://doi.org/10.2527/jas.2010-3694
MARIZANCÉN SMA, Artunduaga PL. 2017. Mejoramiento genético en bovinos a través de la inseminación artificial y la inseminación artificial a tiempo fijo. Revista de Investigación Agraria y Ambiental. 8(2): 247-259. ISSN-e:1989-6352. https://doi.org/10.22490/21456453.2050
MARQUEZINI GHL, Dahlen CR, Bird SL, Lamb GC. 2011. Administration of human chorionic gonadotropin to suckled beef cows before ovulation synchronization and fixed-time insemination: Replacement of gonadotropin-releasing hormone with human chorionic gonadotropin. Journal of Animal Science. 89:3030-3039. ISSN: 1525-3163. https://doi.org/10.2527/jas.2010-3455
MARQUEZINI GHL, Mercadante VRG, Bischoff KM, Black TE, DiLorenzo N, Bird SL. 2013a. Effects of temporary calf removal before fixed-time artificial insemination on pregnancy rates and subsequent calf performance in suckled beef cows. Journal of Animal Science. 91:2414-2425. ISSN: 1525-3163. https://doi.org.10.2527/jas.2012-5743
MARQUEZINI GHL, Mercadante VRG, Olson KC, Jaeger JR, Perry GA, Stevenson JS. 2013b. Effects of equine chorionic gonadotropin on follicle development and pregnancy rates in suckled beef cows with or without calf removal. Journal of Animal Science. 91:1216-1224. ISSN: 1525-3163. https://doi.org/10.2527/jas.2012-5382
MARTIN NT, Thomas JM, Nash JM, Mallory DA, Ellersieck MR, Poock SE. 2014. Comparison of a 16- versus a 19-day o interval between controlled internal drug release removal and prostaglandin F2α following a 14-day controlled internal drug release treatment and fixed-time artificial insemination in postpartum beef cows. Journal of Animal Science. 92:1759-1767. ISSN: 1525-3163. https://doi.org/10.2527/jas.2013-7045
MARTÍNEZ MF, Adams GP, Bergfelt DR, Kastelic JP, Mapletoft RJ. 1999. Effect of LH or GnRH on the dominant follicle of the first follicular wave in beef heifers. Animal Reproduction Science. 57:23-33. ISSN:0378-4320. https://doi.org/10.1016/s0378-4320(99)00057-3
MARTÍNEZ MF, Kastelic JP, Adams GP, Janzen E, McCartney DH, Mapletoft J. 2000. Estrus synchronization and pregnancy rates in beef Cattle given DIP-B, prostaglandin and estradiol, or GnRH. Canadian Veterinary Journal. 41:786-790. ISSN: 0008-5286. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1476379/
MARTÍNEZ MF, Kastelic JP, Adams GP, Mapletoft RJ. 2002. The use of a progesterone –releasing device (DIP-B) or melengestrol acetate with GnRH, LH, or estradiol benzoate for fixed-time AI in beef heifers. Journal of Animal Science. 80:1746-1751. ISSN: 1525-3163. https:/doi.org/10.2527/2002.8071746x
MERCADANTE VRG, Kozicki LE, Ciriaco FM, Henry DD, Dahlen CR, Crosswhite MR. 2015. Effects of administration of protaglandin F2α at initiation of the seven-day CO-Synch+controlled internal drug release ovulation synchronization protocol for suckled beef cows and replacement beef heifers. Journal of Animal Science. 93:5204-5213. ISSN: 1525-3163. https://doi.org/10.2527/jas.2015-8967
MIALOT JP, Constant F, Dezaux P, Grimard B, Deletang F, Ponter AA. 2003. Estrus synchronization in beef cows: comparison between GnRH+PGF2α+GnRH and PRID+PGF2α+eCG. Theriogenology 60:319-330. ISSN: 0093-691X. https://doi.org/10.1016/S0093-691X(02)01371-7
MIHM M, Austin EJ, Good TEM, Ireland JLH, Knight PG, Roche JF. 2000. Identification of potential intrafollicular factors involved in selection of dominant follicles in heifers. Biology of Reproduction. 63:811-819. ISSN: 00063363. https://doi.org/10.1016/S0093-691X(02)01371-7
MOORE K, Thatcher W. 2006. Major advances associated with reproduction in dairy cattle. Journal of Dairy Science. 89:1254-1266. ISSN: 1525-3198. https://doi.org/10.3168/jds.S0022-0302(06)72194-4
MURPHY BD, Martinuk SD. 1991. Equine chorionic gonadotropin. Endocrine Reviews.12:27-44. ISSN: 1945-7189. https://doi.org/10.1210/edrv-12-1-27
NASH JM, Mallory DA, Ellersieck MR, Poock SE, Smith MF, Patterson DJ. 2012. Comparison of long-versus short-term DIP-based protocols to synchronize estrus prior to fixed-time AI in postpartum beef cows. Animal Reproduction Science. 132:11-16. ISSN:0378-4320. https://doi.org/10.1016/j.anireprosci.2012.03.013
NISWENDER GD, Juengel JL, Silva PJ, Rollyson MK, McIntush EW. 2000. Mechanisms controlling the function and life span of the corpus luteum. Physiological Reviews. 80:1-29. ISSN: 1522-1210. https://doi.org/10.1152/physrev.2000.80.1.1
NORONHA IM, Cooke RF, Martins CFG, Oliveira Filho RV, Pohler KG, Vasconcelos JLM. 2020. Administering an additional prostaglandin F2α injection to Bos indicus beef cows during a treatment regimen for fixed-time artificial insemination. Animal Reproduction Science. 219:106535. ISSN: 1873-2232.
https://doi.org/10.1016/j.anireprosci.2020.106535
NÚÑEZ-OLIVERA R, Cuadro F, Bosolasco D, de Brun V, de la Mata J, Brochado C, Meikle A, Bó GA, Menchaca A. 2020. Effect of equine chorionic gonadotropin (eCG) administration and proestrus length on ovarian response, uterine functionality and pregnancy rate in beef heifers inseminated at a fixed-time. Theriogenology. 15;151:16-27. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2020.03.031
NÚÑEZ-OLIVERA R, Bó GA, Menchaca A. 2022. Association between length of proestrus, follicular size, estrus behavior, and pregnancy rate in beef heifers subjected to fixed-time artificial insemination. Theriogenology. 15;181:1-7. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2021.12.028
OLIVEIRA FILHO RV, Cooke RF, de Mello GA, Pereira VM, Vasconcelos JLM, Pohler KG. 2020. The effect of clitoral stimulation post artificial insemination on pregnancy rates of multiparous Bos indicus beef cows submitted to estradiol/progesterone-based estrus synchronization protocol. Journal of Animal Science. 7:1-5. ISSN 1525-3163. https://doi.org/10.1093/jas/skaa195
OOSTHUIZEN N, Canal LB, Fontes PLP, Sanford CD, Dilorenzo N, Dahlen CR. 2018a. Prostaglandin F-2 alpha, 7 d prior to initiation of the 7-d CO-synch plus DIP protocol failed to enhance estrus response and pregnancy rates in beef heifers. Journal of Animal Science. 96:1466-1473. ISSN: 1525-3163. https://doi.org/10.1093/jas/sky058
OOSTHUIZEN N, Fontes PLP, Sanford CD, Ciriaco FM, Henry DD, CANAL LB. 2018b. Estrus synchronization and fixed-time artificial insemination alter calving distribution in Bos indicus influenced beef heifers. Theriogenology. 106:210-213. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2017.10.028
OOSTHUIZEN N, Lansford AC, Canal LB, Fontes PLP, Sanford CD, Dahlen CR. 2018c. Comparison of two alternate PGF (2 alpha) products in two estrus synchronization protocols in beef heifers. Journal of Animal Science. 96:1388-1395. ISSN: 1525-3163. https://doi.org/10.1093/jas/sky059
PERRY GA. 2016. Factors affecting puberty in replacement beef heifers. Theriogenology. 86:373-378. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2016.04.051
PESSOA GA, Martini AP, Carloto GW, Rodrigues MC, Claro-Júnior I, Baruselli PS. 2016. Different doses of equine chorionic gonadotropin on ovarian follicular growth and pregnancy rate of suckled Bos Taurus beef cows subjected to timed artificial insemination protocol. Theriogenology. 15:792-799. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2015.09.057
PFEIFER LF, Castro NA, Melo VT, Neves PM, Cestaro JP, Schneider A. 2015. Timed artificial insemination in blocks: A new alternative to improve fertility in lactating beef cows. Animal Reproduction Science. 163 :89-96. ISSN:0378-4320.
https://doi.org/10.1016/j.anireprosci.2015.10.002
PFEIFER LF, Leonardi CE, Castro NA, Viana JH, Siqueira LG, Castilho EM. 2014.The use of PGF2α as ovulatory stimulus for timed artificial insemination in cattle. Theriogenology. 15:81:689-695. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2013.11.016
PFEIFER LFM, Gasperin BG, Cestaro JP, Schneider A. 2022. Postponing TAI in beef cows with small preovulatory follicles. Animal Reproduction Science. 242:107006. ISSN: 1873-2232. https://doi.org/10.1016/j.anireprosci.2022.107006
PINTO HF, Missio D, Dos Santos Brum D, Carloto GW, Martini AP, Pessoa GA, Neto NA, Claro I Jr, Sá Filho MF, Leivas FG. Decreasing the dose of equine chorionic gonadotropin does not affect ovarian or pregnancy responses of purebred taurine and crossbred beef heifers. Animal Reproduction Science. 218:106474. ISSN: 1873-2232. https://doi.org/10.1016/j.anireprosci.2020.106474
RANDI F, Kelly AK, Parr MH, Diskin MG, Lively F, Lonergan P, Kenny DA.2021. Effect of ovulation synchronization program and season on pregnancy to timed artificial insemination in suckled beef cows. Theriogenology. 15;172:223-229. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2021.06.021
RATHBONE MJ, Kinder JE, Fike K, Kojima F, Clopton D, Ogle CR. 2001. Recent advances in bovine reproductive endocrinology and physiology and their impact on drug delivery system design for the control of the estrous cycle in cattle. Advanced. Drug Delivery Reviews. 50:277-320. ISSN: 1872-8294. https://doi.org/10.1016/s0169-409x(01)00156-9
REINERI PS, Bernhard SDR, Principi SA, Gerlero GD, Aller JF. 2023. Effects of two protocols of ovulation synchronization on corpus luteum size and blood flow, progesterone concentration, and pregnancy rate in beef heifers. Animal Reproduction Science. 251:107223. ISSN: 1873-2232. https://doi.org/10.1016/j.anireprosci.2023.107223
RODGERS RJ, Rodgers HFI. 2010. Morphological classification of bovine ovarian follicles. Reproduction Review. 139:309-318. ISSN: 1741-7899. https://doi.org/10.1530/REP-09-0177
RODRIGUES AD, Cooke RF, Cipriano RS, Silva LGT, Cerri RLA, Cruppe LH. 2018. Impacts of estrus expression and intensity during a timed-AI protocol on variables associated with fertility and pregnancy success in Bos indicus-influenced beef cows. Journal of Animal Science. 96(1):236-249. ISSN: 1525-3163.
https://doi.org/10.1093/jas/skx043
RODRIGUEZ AM, Maresca S, López-Valiente S, Bilbao MG, Moran KD, Bartolome JA, Pratt SL, Long NM. 2023. Comparison of the 7-day CO-Synch and 8-day estradiol-based protocols for estrus synchronization and timed artificial insemination in suckled Bos taurus cows. Theriogenology. 1;200:70-76. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2023.02.003
ROJAS-CANADAS E, Battista SE, Kieffer JD, Wellert SR, Mussard ML, Garcia-Guerra A. 2023. GnRH dose at initiation of a 5-day CO-Synch + P4 for fixed time artificial insemination in suckled beef cows. Animal Reproduction Science. 250:107210. ISSN: 1873-2232J. https://doi.org/10.1016/j.anireprosci.2023.107210
ROSALES-TORRES AM, GUZMÁN A. 2008. Apoptosis in follicular atresia and luteal regression. Review. Técnica Pecuaria en México. 46:159-182. ISSN: 0040-1889. https://www.redalyc.org/pdf/613/61346205.pdf
ROSALES-TORRES AM, Guzmán A, Gutiérrez AC. 2012. Follicular development in domestic ruminants. Tropical and Subtropical Agroecosystems. 1:147–160. https://www.revista.ccba.uady.mx/ojs/index.php/TSA/article/view/1299/709
ROSALES-TORRES AM, Guzmán-Sánchez A. 2011. Role of Vascular Endothelial Growth Factor and its receptors during the ovarian cycle. Review. Revista Mexicana de Ciencias Pecuarias. 3(1):89-111. ISSN: 2448-6698.
https://www.redalyc.org/pdf/2656/265622705008.pdf
ROSALES-TORRES AM, López–Cedillo Z.B, Hernández-Coronado CG. Rosete-Fernández JV, Mendoza GD, Guzmán A. 2017. Short-term dietary concéntrate supplementation during estrus synchronization treatment in beef cows increased IGF-I serum concentration but did not affect the reproductive respons. Tropical Animal Health and Production. 49: 221-226. ISSN: 15737438. https://doi.org/10.1007/s11250-016-1166-7
ROSS PJ, Aller JF, Callejas SS, Butler H, Alberio RH. 2004. Estradiol benzoate given 0 or 24 h after the end of a progestagen treatment in postpartum suckled beef cows. Theriogenology. 62:265-273. ISSN: 0093-691X.
https:doi.org/10.1016/j.theriogenology.2003.10.013
SA FILHO MF, Crespilho AM, Santos JE, Perry GA, Baruselli PS. 2010. Ovarian follicle diameter at timed insemination and estrous response influence likelihood of ovulation and pregnancy after estrous synchronization with progesterone or progestin-based protocols in suckled Bos indicus cows. Animal Reproduction Science. 120(1-4):23-30. ISSN:0378-4320. https://doi.org/10.1016/j.anireprosci.2010.03.007
SALES JNS, Carvalho JBP, Crepaldi GA, Cipriano RS, Jacomini JO, Maio JRG. 2012. Effects of two estradiol esters (benzoate and cypionate) on the induction of synchronized ovulations in Bos indicus cows submitted to a timed artificial insemination protocol. Theriogenology. 78:510-516. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2012.02.031
SANTOS MH, Ferraz Junior MVC, Polizel DM, Barroso JPR, Miszura AA, Martins AS, and Bertoloni AV. 2018. Decreasing from 9 to 7 days the permanence of progesterone inserts makes possible their use up to 5 folds in suckled Nellore cows. Theriogenology. 111:56-61. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2018.01.017
SARTORI R, Barros CM. 2011. Reproductive cycles in Bos indicus cattle. Animal Reproduction Science. 124 :244-250. ISSN:0378-4320.
https://doi.org/10.1016/j.anireprosci.2011.02.006
SARTORI R, Haughian JM, Shaver RD, Rosa GJM, Wiltbank MC. 2004. Comparison of Ovarian Function and Circulating Steroids in Estrous Cycles of Holstein Heifers and Lactating. Journal of Dairy Science. 87:905-920. ISSN: 1525-3198.
https://doi.org/10.3168/jds.S0022-0302(04)73235-X
SCARPA JO, O’neil MM, Cardoso RC, Stanko RL, Williams GL. 2019. Ovarian follicular and luteal characteristics in Bos indicus-influenced beef cows using prostaglandin F2α with or without GnRH at the onset of the 5-day CO-Synch + controlled internal drug release (DIP) protocol. Animal Reproduction Science. 204:1-9. ISSN:0378-4320. https://doi.org/10.1016/j.anireprosci.2019.02.013
SCHAFER DJ, Bader JF, Meyer JP, Haden JK, Ellersieck MR, Lucy MC. 2007. Comparison of preogestin-based protocols to synchronize estrus and ovulation before fixed-time artificial insemination in postpartum beef cows. Journal of Animal Science. 85:1940-1945. ISSN: 1525-3163. https://doi.org/10.2527/jas.2006-836
SHIRASUNA K, Nitta A, Sineenard J, Shimizu T, Bollwein H, Miyamoto A. 2012. Vascular and immune regulation of corpus luteum development, maintenance, and regression in the cow. Domestic Animal Endocrinology. 43(2):198-211. ISSN: 18790054. https://doi.org/10.1016/j.domaniend.2012.03.007
SILVA MAV, Santos CS, Franca IG, Pereira HG, Sa Filho MF, FREITAS BG. 2018a. Hormonal strategy to reduce suckled beef cow handling for timed artificial insemination with sex-sorted semen. Theriogenology. 114:159-164. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2018.03.020
SILVA EP, Wiltbank MC, Machado AB, Gambin LS, Dias MM, Chaiben MFC. 2018b. Optimizing timed AI protocols for Angus beef heifers: Comparison of induction of synchronized ovulation with estradiol cypionate or GnRH. Theriogenology. 121:7-12. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2018.07.019
SIMÕES L MS, Orlandi RE, Massoneto JPM, Scandiuzzi LA Jr, Freitas BG, Bastos MR, Souza JC, Sales JNS. 2018. Exposure to progesterone previous to the protocol of ovulation synchronization increases the follicular diameter and the fertility of suckled Bos indicus cows. Theriogenology. 116:28-33. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2018.04.031
SIRARD MA. 2016. Somatic environment and germinal differentiation in antral follicle: The effect of FSH withdrawal and basal LH on oocyte competence acquisition in cattle. Theriogenology. 86(1):54-61. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2016.04.018
SIROIS J, Fortune JE. 1988. Ovarian Follicular Dynamics during the Estrous Cycle in Heifers Monitored by Real-Time UItrasonography. Biology of Reproduction. 39:308-317. ISSN:00063363. https:/doi.org/10.1095/biolreprod39.2.308
SMALL JA, Colazo MG, Kastelic JP, Mapletoft RJ. 2009. Effect of progesterone presynchronization and eCG on pregnancy rates to GnRH-based, timed-AI in beef cattle. Theriogenology. 71:698-706. ISSN: 0093-691X.
https://doi.org/10.1016/j.theriogenology.2008.09.045
SPECKHART SL, Oliveira Filho RV, Franco GA, Vasconcelos JLM, Schrick FN, Edwards JL, Pohler KG. 2022. Short Communication: Influence of estrus activity and reproductive tract size and position scores on fertility in Bos indicus and Bos taurus suckled beef cows. Journal of Animal Science. 100(6):skac141. ISSN 1525-3163.
https://doi.org/10.1093/jas/skac141
STEGNER JE, Bader JF, Kojima, FN, Ellersieck MR, Smith MF, Petterson DJ. 2004. Fixed-time artificial insemination of postpartum beef cows at 72 or 80 h after treatment with the MGA® Select protocol. Theriogenology. 61:1299-1305. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2003.07.023
STEVENSON JS, Lamb GC, Jhonson MA, Medina-Britos MA, Grieger DM, Harmoney, KR. 2003. Supplemental norgestomet, progesterone, or melengestrol acetate increases pregnancy rates in suckled beef cows after timed inseminations. Journal of Animal Science. 81:571-586. ISSN: 1525-3163. https://doi.org/10.2527/2003.813571x
THOMAS JM, Locke JWC, Bishop BE, Abel JM, Ellersieck MR, Yelich JV. 2017. Evaluation of the 14- DIP-PG and 9-d DIP-PG protocols for synchronization of estrus in Bos indicus-influenced and Bos taurus beef heifers. Theriogenology. 92:190-196. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2017.01.020
THOMAS JM, Poock SE, Ellersieck MR, Smith MF, Patterson DJ. 2014. Delayed insemination for non-estrous heifers and cows when using conventional semen in timed artificial insemination. Journal of Animal Science. 92:4189-4197. ISSN: 1525-3163.
https://doi.org/10.2527/jas.2014-7827
USLENGHI G, Chaves SG. Cabodevila J, Callejas S. 2014. Effect of estradiol cypionate and amount of progesterone in the intravaginal device on synchronization of estrus, ovulation and on pregnancy rate in beef cows treated with FTAI based protocols. Animal Reproduction Science. 145:1-7. ISSN:0378-4320.
https://doi.org/10.1016/j.anireprosci.2013.12.009
USLENGHI G, Vater A, Rodríguez-Aguilar S, Cabodevila J, Callejas S. 2016. Effect of estradiol cypionate and GnRH treatment on plasma estradiol-17β concentrations, synchronization of ovulation and on pregnancy rates in suckled beef cows treated with FTAI-based protocols. Reproduction in Domestic Animals. 51(5):693-699. ISSN: 1439-0531. https://doi.org/10.1111/rda.12732
WEBB R, Garnsworthy PC, Gong JG, Armstrong DG. 2004. Control of follicular growth: Local interactions and nutritional influences1,2. Journal of Animal Science. 82:E63-E74. ISSN: 1525-3163. https:doi.org/10.2527/2004.8213_supplE63x
WENZINGER B, Bleul U, 2012. Effect of a prostaglandin F2α analogue on the cyclic corpus luteum during its refractory period in cows. BMC Veterinary Research. 14:8:220. ISSN: 1746-6148. https://doi.org/10.1186/1746-6148-8-220
WHITE SS, Kasimanickam RK, Kasimanickam VR. 2016. Fertility after two doses of PGF2α concurrently or at 6-hour interval on the day of DIP removal in 5-day CO-Synch progesterone-based synchronization protocols in beef heifers. Theriogenology. 86:785-790. ISSN: 0093-691X. https:// doi.org/10.1016/j.theriogenology.2016.02.032
WHITTIER WD, Currin JF, Schramm H, Holland S. 2013. Fertility in Angus cross beef cows following 5-day CO-Synch+DIP or 7-day CO-Synch estrus synchronization and timed artificial insemination. Theriogenology. 80:963-969. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2013.07.019
WHITTIER WD, Kasimanickam RK, Currin JF, Schramm HH, Vlcek M., 2010. Effect of timing of second prostaglandin F2α administration in a 5-day, progesterone-based Co- Synch protocol on AI pregnancy rates in beef cows. Theriogenology. 74:1002-1009. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2010.04.029
WILLIAMS GL, Stanko, RL. 2020. Pregnancy rates to fixed-time AI in Bos indicus-influenced beef cows using PGF2α with (Bee Synch I) or without (Bee Synch II) GnRH at the onset of the 5-day Co-Synch+DIP protocol. Theriogenology. 142:229-235. ISSN: 0093-691X. https://doi.org/10.1016/j.theriogenology.2019.09.047
WILSON DJ, Mallory, DA, Busch DC, Leitman NR, Haden JK, Schafer DJ. 2010. Comparison of short-term progestin-based protocols to synchronize estrus and ovulation in postpartum beef cows. Journal of Animal Science. 88:2045-2054. ISSN: 1525-3163. https://doi.org/10.2527/jas.2009-2627
ZWIEFELHOFER EM, Macmillan K, Gobikrushanth M, Adams GP, Yang SX, Anzar M, Asai-Coakwell M, Colazo MG. 2021. Comparison of two intravaginal progesterone-releasing devices in shortened-timed artificial insemination protocols in beef cattle. Theriogenology. 1;168:75-82. ISSN: 0093-691X.