La ubre de la cabra: mecanismo de secreción láctea y síntesis de proteínas/grasas

Autores/as

Palabras clave:

glándula mamaria, leche de cabra, lipogénesis, proteogénesis

Resumen

En los últimos años, el cambio en la comercialización de la leche hacia una estructura de precios estandarizada a partir de los componentes lácteos ha puesto un mayor énfasis en la concentración lipídica y proteica sobre la cantidad de L o kg de leche producidos. En virtud de lo anterior, el contenido nutricional de la leche de cabra supera al contenido nutricional de la leche de vaca, en lo que respecta a proteínas y grasas, y son los lactocitos de la gandula mamaria caprina, quienes deben replicarse y sintetizar estos componentes lácteos. Por lo tanto, esta revisión considera de manera inicial la comprensión de la anatomía e histología de la glándula mamaria como responsable de todas las actividades vinculadas al mecanismo de eyección de la leche. El desarrollo de la glándula mamaria determina todos los aspectos del comportamiento celular, por lo que se revisa su desarrollo a través de cuatro etapas: i) mamogénesis, ii) lactogénesis, iii) galactopoyesis, y iv) involución. El resto de la revisión hace hincapié en la lipogénesis y la proteogenesis láctea, debido a sus diversas funciones dentro del metabolismo celular y la producción de la fracción lipídica y fracción proteica de la leche.

e2023-1

http://dx.doi.org/10.21929/abavet2023.10

https://www.youtube.com/watch?v=2c5yTNp4hmA 

Citas

AHERN K. 2019. Amino acids: 20 building blocks of life. In: Ahern K, Biochemistry and Molecular Biology: How Life Works. Virginia, United States: The Teaching Company. Pp. 29-40. ISBN: 978-1-25-983793-7.

https://www.thegreatcourses.com/courses/biochemistry-and-molecular-biology-how-life-works

ANGOV E. 2011. Codon usage: nature's roadmap to expression and folding of proteins. Biotechnology Journal. 6(6):650-659. ISSN: 1860-7314.

https://doi.org/10.1002/biot.201000332

APPLETON A, Vanbergen O, Dominiczak MH. 2013a. Metabolismo de las proteínas. En: Horton-Szar D, Lo Esencial en Metabolismo y Nutrición. Barcelona, España: Elsevier Health Sciences. Pp. 71-82. ISBN: 978-0-7234-3626-3.

https://www.elsevier.com/books/lo-esencial-en-metabolismo-y-nutricion/978-84-9113-537-1

APPLETON A, Vanbergen O, Dominiczak MH. 2013b. Metabolismo energético I: ciclo ATC. En: Horton-Szar D, Lo Esencial en Metabolismo y Nutrición. Barcelona, España: Elsevier Health Sciences. Pp. 13-17. ISBN: 978-0-7234-3763-5.

https://www.elsevier.com/books/lo-esencial-en-metabolismo-y-nutricion/978-84-9113-537-1

APPLETON A, Vanbergen O, Dominiczak MH. 2013c. Metabolismo energético II: generación de ATP. En: Horton-Szar D, Lo Esencial en Metabolismo y Nutrición. Barcelona, España: Elsevier Health Sciences. Pp. 17-23. ISBN: 978-0-7234-3763-5. https://www.elsevier.com/books/lo-esencial-en-metabolismo-y-nutricion/978-84-9113-537-1

APPLETON A, Vanbergen O, Dominiczak MH. 2013d. Transporte y metabolismo de los lípidos. En: Horton-Szar D, Lo Esencial en Metabolismo y Nutrición. Barcelona, España: Elsevier Health Sciences. Pp. 45-70p. ISBN: 978-0-7234-3626-3. https://www.elsevier.com/books/lo-esencial-en-metabolismo-y-nutricion/978-84-9113-537-1

ASHDOWN RR, Done SH. 2011. La ubre. En: Ashdown RR, Atlas en color de anatomía veterinaria. Rumiantes. Barcelona, España: Elsevier Health Science Division. Pp. 219-230. ISBN: 9788480865418. https://catalogo.udes.edu.co/cgi-bin/koha/opac-detail.pl?biblionumber=31192

BALJIT S. 2017. Ruminants / the udder. In: Baljit S, Dyce, Sack and Wensing's Textbook of Veterinary Anatomy. New York, EE. UU.: Elsevier Health Science Division. Pp. 1252-1264. ISBN: 978-0323442640. https://www.elsevier.com/books/dyce-sack-and-wensings-textbook-of-veterinary-anatomy/singh/978-0-323-44264-0

BALLA T, Kim YJ, Alvarez-Prats A, Pemberton J. 2019. Lipid dynamics at contact sites between the endoplasmic reticulum and other organelles. Annual Review of Cell and Developmental Biology. 35(1):85-109. ISSN: 1530-8995. https://doi.org/10.1146/annurev-cellbio-100818-125251

BAUMAN DE, Mather IH, Wall RJ, Lock AL. 2006. Major advances associated with the biosynthesis of milk. Journal of Dairy Science. 89(4):1235-1243. ISSN: 1525-3198. https://doi.org/10.3168/jds.S0022-0302(06)72192-0

BELEW GD, Silva J, Rito J, Tavares L, Viegas I, Teixeira J, Oliveira PJ, Macedo MP, Jones JG. 2019. Transfer of glucose hydrogens via acetyl-CoA, malonyl-CoA, and NADPH to fatty acids during de novo lipogenesis. Journal of Lipid Research. 60(12):2050-2056. ISSN: 1539-7262. https://doi.org/10.1194/jlr.RA119000354

BELO CJ, Bruckmaier RM. 2010. Suitability of low-dosage oxytocin treatment to induce milk ejection in dairy cows. Journal of Dairy Science. 93(1):63-69. ISSN: 1525-3198. https://doi.org/10.3168/jds.2009-2084

BOTHAM MK, Mayes AP. 2018a. Bioenergetics: the role of ATP. In: Rodwell WV, Bender AD, Botham MK, Kennelly JP , Weil AP, Harper’s Illustrated Biochemistry. United States: McGraw-Hill Education / Medical. Pp. 277-291. ISBN: 978-1-25-983793-7. https://accessmedicine.mhmedical.com/book.aspx?bookID=2386

BOTHAM MK, Mayes AP. 2018b. Lipids of physiological significance. In: Rodwell WV, Bender AD, Botham MK, Kennelly JP , Weil AP, Harper’s Illustrated Biochemistry. United States: McGraw-Hill Education / Medical. Pp. 483-511. ISBN: 978-1-25-983793-7. https://accessmedicine.mhmedical.com/book.aspx?bookID=2386

BRUCKMAIER RM, Wellnitz O. 2008. Induction of milk ejection and milk removal in different production systems. Journal of Animal Science. 86(13 Suppl):15-20. ISSN: 1525-3163. https://doi.org/10.2527/jas.2007-0335

CHANDEL NS. 2021. Lipid metabolism. Cold Spring Harbor Perspectives in Biology. 13(9):34-41. ISSN: 1943-0264 https://doi.org/10.1101/cshperspect.a040576

COOPER GM. 2019a. The biosynthesis of cell constituents. Carbohydrates, lipids, proteins, adn nucleic acids. In: Cooper GM, The Cell: A Molecular Approach. Oxford, New York: Oxford University Press. Pp. 102-111. ISBN: 978-1-60535-707-2. https://learninglink.oup.com/access/cooper8e

COOPER GM. 2019b. Eukaryotic RNA polymerases and general transcription factors. In: Cooper GM, The Cell: A Molecular Approach. Oxford, New York: Oxford University Press. Pp. 258-276. ISBN: 978-1-60535-707-2. https://learninglink.oup.com/access/cooper8e

DAVIDSON PA, Stabenfeldt HG. 2020. The mammary gland and lactation. In: Klein BG, Cunningham’s Textbook of Veterinary Physiology. St. Louis, Missouri: Elsevier Health Science Division. Pp. 458-471. ISBN: 978-0-323-55227-1. https://www.elsevier.com/books/cunningham's-textbook-of-veterinary-physiology/978-0-323-55227-1

DEE FA, Magee C. 2018. Anatomy and physiology of the mammary gland. In: Iowa State University Press, Anatomy and Physiology of Farm Animals. Iowa, EE. UU.: Wiley Blackwell. Pp. 501-515. ISBN: 9780813813943. https://www.wiley.com/en-ie/Anatomy+and+Physiology+of+Farm+Animals%2C+8th+Edition-p-9781119239765

DHASMANA S, Das S, Shrivastava S. 2022. Potential nutraceuticals from the casein fraction of goat's milk. Journal of Food Biochemistry. 46(6):e13982. ISSN: 1745-4514. https://doi.org/10.1111/jfbc.13982

DIAO M, Liang Y, Zhao J, Zhang J, Zhang T. 2022. Complexation of ellagic acid with α-lactalbumin and its antioxidant property. Food Chemistry. 372(1):131307. ISSN: 1873-7072. https://doi.org/10.1016/j.foodchem.2021.131307

DOHERTY EA, Doudna JA. 2000. Ribozyme structures and mechanisms. Annual Review of Biochemistry. 69:597-615. ISSN: 0066-4154.

https://doi.org/10.1146/annurev.biochem.69.1.597

ELLIS JM, Bowman CE, Wolfgang MJ. 2015. Metabolic and tissue-specific regulation of acyl-CoA metabolism. PLOS ONE. 10(3):e0116587. ISSN: 1932-6203. https://doi.org/10.1371/journal.pone.0116587

FERNANDEZ RF, Ellis JM. 2020. Acyl-CoA synthetases as regulators of brain phospholipid acyl-chain diversity. Prostaglandins Leukot Essent Fatty Acids. 161(1):102-115. ISSN: 1532-2823. https://doi.org/10.1016/j.plefa.2020.102175

FOX PF, Lowe UT, McSweeney PLH, O'Mahony JA. 2015. Structure and development of mammary tissue. In: Fox PF , McSweeney PLH, Dairy Chemistry and Biochemistry. New York, United States: Springer International Publishing. Pp.1-7. ISBN: 978-3-319-14892-2. https://link.springer.com/book/10.1007/978-3-319-14892-2

FRIEDMAN JR, Nunnari J. 2014. Mitochondrial form and function. Nature. 505(7483):335-343. ISSN: 1476-4687. https://doi.org/10.1038/nature12985

GARTNER LP. 2018. The cell and the organelles. In: Vosburgh A , Horvath K, Color atlas and text of histology. Philadelphia, United States: Lippincott Williams & Wilkins. Pp. 17-26. ISBN: 9781496346735 https://meded.lwwhealthlibrary.com/book.aspx?bookid=2066

GOFF PJ. 2015. Endocrinology, reproduction, and lactation/The mammary gland and lactation. In: Reece OW, Erickson HH, Goff PJ , Uemura EE, Dukes' Physiology of Domestic Animals. New York, EE. UU.: John Wiley & Sons. Pp. 617-727. ISBN: 978‐0‐1185‐0139‐9/2015. https://www.wiley.com/en-us/Dukes%27+Physiology+of+Domestic+Animals%2C+13th+Edition-p-9781118501399

GUOYAO W. 2017a. Chemistry of lipids. In: Guoyao W, Principles of Animal Nutrition. New York, United States: CRC Press. Pp. 109-142. ISBN: 978-1-4987-2160-8. https://www.routledge.com/Principles-of-Animal-Nutrition/Wu/p/book/9781032095998

GUOYAO W. 2017b. Nutrition and metabolism of protein and amino acids. In: Guoyao W, Principles of Animal Nutrition. New York, United States: CRC Press. Pp. 349-411. ISBN: 978-1-4987-2160-8. https://www.routledge.com/Principles-of-Animal-Nutrition/Wu/p/book/9781032095998

HARVATINE KJ, Boisclair YR, Bauman DE. 2009. Recent advances in the regulation of milk fat synthesis. Animal. 3(1):40-54. ISSN: 1751-732X.

https://doi.org/10.1017/S1751731108003133

HEID HW, Keenan TW. 2005. Intracellular origin and secretion of milk fat globules. European Journal of Cell Biology. 84(2-3):245-258. ISSN: 0171-9335.

https://doi.org/10.1016/j.ejcb.2004.12.002

HENNA K, Boudjellaba S, Khammar F, Amirat Z, Chesneau D, Charallah S. 2021. Endocrine, energy, and lipid status during parturition and early lactation in indigenous goats native to the Algerian Sahara. Veterinary World. 14(9):2419-2426. ISSN: 0972-8988. https://doi.org/10.14202/vetworld.2021.2419-2426

HENRY C, Saadaoui B, Bouvier F, Cebo C. 2015. Phosphoproteomics of the goat milk fat globule membrane: New insights into lipid droplet secretion from the mammary epithelial cell. Proteomics. 15(13):2307-2317. ISSN: 1615-9861.

https://doi.org/10.1002/pmic.201400245

INGOLIA NT. 2014. Ribosome profiling: new views of translation, from single codons to genome scale. Nature Reviews Genetics. 15(3):205-213. ISSN: 1471-0064.

https://doi.org/10.1038/nrg3645

JOHN PAT, van Schie SNS, Cheung NJ, Michel AH, Peter M, Kornmann B. 2022. Rewiring phospholipid biosynthesis reveals resilience to membrane perturbations and uncovers regulators of lipid homeostasis. Journal of the European Molecular Biology Organization. 41(7):e109998. ISSN: 1460-2075.

https://doi.org/10.15252/embj.2021109998

JONES JG. 2016. Hepatic glucose and lipid metabolism. Diabetologia. 59(6):1098-1103. ISSN: 1432-0428 https://doi.org/10.1007/s00125-016-3940-5

KUMAR S, Puniya AK, Puniya M, Dagar SS, Sirohi SK, Singh K, Griffith GW. 2009. Factors affecting rumen methanogens and methane mitigation strategies. World Journal of Microbiology & Biotechnology. 25(9):1557-1566. ISSN: 0959-3993.

https://doi.org/10.1007/s11274-009-0041-3

LACASSE P, Lollivier V, Bruckmaier RM, Boisclair YR, Wagner GF, Boutinaud M. 2011. Effect of the prolactin-release inhibitor quinagolide on lactating dairy cows. Journal of Dairy Science. 94(3):1302-1309. ISSN: 1525-3198. https://doi.org/10.3168/jds.2010-3649

LAWHEAD BJ, Baker M. 2017. The endocrine system/endocrine glands. In: Lawhead BJ, Baker M, Introduction to Veterinary Science. Wisconsin Madison, EE. UU.: Cengage Learning. Pp. 169-179. ISBN: 978-1-1115-4279-5..

https://www.cengagebrain.com.mx/shop/isbn/9781111542795

LÉRIAS RJ, Hernández CLE, Suárez TA, Castro N, Pourlis A, Almeida AM. 2014. The mammary gland in small ruminants: major morphological and functional events underlying milk production-a review. Journal of Dairy Research. 81(3):304-318. ISSN: 1469-7629. https://doi.org/10.1017/S0022029914000235

LOWE M. 2011. Structural organization of the Golgi apparatus. Current Opinion in Cell Biology. 23(1):85-93. ISSN: 1879-0410. https://doi.org/10.1016/j.ceb.2010.10.004

LOZANO JA, Galindo JD, García BJC, Martínez LJH, Peñafiel GR, Solano MF. 2005. Metabolismo nitrogenado. En: Lozano JA, Bioquímica y Biología Molecular para Ciencias de la Salud. Barcelona, España: McGraw-Hill Interamericana. Pp. 275-302. ISBN: 4-486-0642-68. https://jabega.uma.es/discovery/fulldisplay/alma991000078319704986/34CBUA_UMA:VU1

LUNDQUIST PK, Shivaiah KK, Espinoza-Corral R. 2020. Lipid droplets throughout the evolutionary tree. Progress in Lipid Research. 78(1):101-109. ISSN: 1873-2194. https://doi.org/10.1016/j.plipres.2020.101029

MADIGAN TM, Bender SK, Buckley HD, Sattley WM, Stahl AD. 2019a. Biosyntheses. Sugars and polysaccharides. Amino acids and nucleotides. Fatty acids and lipids. In: Madigan TM, Brock Biology of Microorganisms. New York, United States: Pearson. Pp. 130-137. ISBN: 978-1-292-23510-3. https://www.pearson.com/en-us/subject-catalog/p/brock-biology-of-microorganisms/P200000006867/9780135860717

MADIGAN TM, Bender SK, Buckley HD, Sattley WM, Stahl AD. 2019b. Protein synthesis: translation. In: Madigan TM, Brock Biology of Microorganisms. New York, United States: Pearson. Pp. 156-170. ISBN: 978-1-292-23510-3 https://www.pearson.com/en-us/subject-catalog/p/brock-biology-of-microorganisms/P200000006867/9780135860717

MALDONADO JJA, Salinas GH, Torres HG, Becerril PCM, P. DR. 2018. Factors influencing milk production of local goats in the Comarca Lagunera, Mexico. Livestock Research for Rural Development. 30(7):2-7. ISSN: 0121-3784.

https://www.cabdirect.org/cabdirect/abstract/20183317336

MANTEROLA BH. 2011. Estrategias nutricionales y alimenticias para modificar los sólidos totales de la leche. En Seminario sobre productividad en sistemas pastoriles lecheros. Departamento de Producción Animal, (Ed.). Págs. 1-20. Circular de Extensión. Facultad de Ciencias Agronómicas, Universidad de Chile.

https://www.paislobo.cl/2011/10/seminario-sobre-productividad-en.html

MARTÍNEZ GM, Suárez VH. 2018. The mammary gland: morphology and development. Synthesis of milk components. In: Martínez GM , Suárez VH, Goat dairying: production, management, health, quality of milk and products. Buenos Aires, Argentina: Ediciones INTA. Pp. 37-41. ISBN: 978-987-521-972-4.

https://repositorio.inta.gob.ar/xmlui/handle/20.500.12123/5408?locale-attribute=en

MAS OJ. 2018. Metabolismo de los lípidos. En: Hernández MMT, Bioquímica de Laguna y Piña. Ciudad de México, México: El Manual Moderno. Pp. 660-713. ISBN: 978-607-448-708-4. https://libros.facmed.unam.mx/index.php/2021/07/22/bioquimica-de-laguna-y-pina/

MCDONALD P, Edwards RA, Greenhalgh JFD, Morgan CA, Sinclair LA, Wilkinson RG. 2011. Lipids. In: McDonald P, Animal Nutrition. New York, United States: Prentice Hall. Pp. 32-52. ISBN: 978-1408204238. https://www.pearson.com/en-gb/search.html?aq=Mc%20Donald-Animal-Nutrition-7th-Edition

MCKERCHAR HJ, Lento C, Bennie RZ, Crowther JM, Dolamore F, Dyer JM, Clerens S, Mercadante D, Wilson DJ, Dobson RCJ. 2023. The protein dynamics of bovine and caprine β-lactoglobulin differ as a function of pH. Food Chemistry. 408(1):135229. ISSN: 1873-7072. https://doi.org/10.1016/j.foodchem.2022.135229

MENZIES P. 2021. Udder health for dairy goats. Veterinary Clinics of North America: Food Animal Practice. 37(1):149-174. ISSN: 1558-4240.

https://doi.org/10.1016/j.cvfa.2020.12.002

MONKS J, Ladinsky MS, McManaman JL. 2020. Organellar contacts of milk lipid droplets. Thousand Oaks Journal. 3(1):2-12. ISSN: 2515-2564.

https://doi.org/10.1177/2515256419897226

National Chamber of Industrial Milk. 2021. CANILEC. Markets and statistics. http://www.canilec.org.mx/index.html

NAYIK GA, Jagdale YD, Gaikwad SA, Devkatte AN, Dar AH, Ansari MJ. 2022. Nutritional profile, processing and potential products: A comparative review of goat milk. Dairy. 3(3):622-647. ISSN: 2624-862X. https://doi.org/10.3390/dairy3030044

NELSON LD, Cox MM. 2017a. The citric acid cycle. In: Nelson LD , Cox MM, Lehninger. Principles of Biochemistry. New York, United States: Freeman, W. H. Pp. 1668-1743. ISBN: 9781464126116. https://link.springer.com/book/9781319381493

NELSON LD, Cox MM. 2017b. Lipids. In: Nelson LD , Cox MM, Lehninger. Principles of Biochemistry. New York, United States: Freeman, W. H. Pp. 989-1056. ISBN: 9781464126116. https://link.springer.com/book/9781319381493

NELSON LD, Cox MM. 2017c. Protein metabolism. In: Nelson LD , Cox MM, Lehninger. Principles of Biochemistry. New York, United States: Freeman, W. H. Pp. 2820-2941. ISBN: 9781464126116. https://link.springer.com/book/9781319381493

NEVILLE MC, McFadden TB, Forsyth I. 2002. Hormonal regulation of mammary differentiation and milk secretion. Journal of Mammary Gland Biology and Neoplasia. 7(1):49-66. ISSN: 1083-3021. https://doi.org/10.1023/A:1015770423167

NUNES NA, Araujo WL, Obata T, Fernie AR. 2013. Regulation of the mitochondrial tricarboxylic acid cycle. Current Opinion in Plant Biology. 16(3):335-343. ISSN: 1879-0356. https://doi.org/10.1016/j.pbi.2013.01.004

OLARTE MJ, Kim S, Sharp ME, Swanson JMJ, Farese RV, Jr., Walther TC. 2020. Determinants of endoplasmic reticulum-to-lipid droplet protein targeting. Developmental Cell. 54(4):471-487 e477. ISSN: 1878-1551. https://doi.org/10.1016/j.devcel.2020.07.001

PACHECO GV, Caballero ZA, Martínez GS, Prado ROF, García CAC. 2021. Biochemistry and metabolic pathways of polysaccharides, lipids, and proteins. Abanico Veterinario. 11(1):1-26. ISSN: 2448-6132. https://doi.org/10.21929/abavet2021.47

PHILIPPS WP. 2018. Proteases-general aspects. In: Simões NC , Kumar V, Enzymes in Human and Animal Nutrition: Principles and Perspectives. New York, United States: Academic Press. Pp. 257-264. ISBN: 9780128094266.

https://shop.elsevier.com/books/enzymes-in-human-and-animal-nutrition/nunes/978-0-12-805419-2

PIÑA GE, Flores HO. 2018. Metabolismo de los compuestos nitrogenados. En: Hernández MMT, Bioquímica de Laguna y Piña. Ciudad de México, México: El Manual Moderno. Pp. 714-763. ISBN: 978-607-448-708-4. https://libros.facmed.unam.mx/index.php/2021/07/22/bioquimica-de-laguna-y-pina/

POL A, Gross SP, Parton RG. 2014. Review: biogenesis of the multifunctional lipid droplet: lipids, proteins and sites. Journal of Cell Biology. 204(5):635-646. ISSN: 1540-8140. https://doi.org/10.1083/jcb.201311051

REECE OW, Rowe WE. 2017a. Endocrine system. In: Reece OW, Rowe WE, Functional Anatomy and Physiology of Domestic Animals. New York, United States: John Wiley & Sons. Pp. 242-262. ISBN: 9781119270843. https://www.wiley.com/en-us/Functional+Anatomy+and+Physiology+of+Domestic+Animals%2C+5th+Edition-p-9781119270867

REECE OW, Rowe WE. 2017b. Lactation / functional anatomy of female mammary glands. Mammogenesis, lactogenesis and lactation. In: Reece OW, Rowe WE, Functional Anatomy and Physiology of Domestic Animals. New York, EE. UU.: John Wiley & Sons. Pp. 660-678. ISBN: 9781119270843. https://www.wiley.com/en-us/Functional+Anatomy+and+Physiology+of+Domestic+Animals%2C+5th+Edition-p-9781119270867

REESE OW, Budras KD, Mülling C, Bragulla H, Hagen J, Witter K, König HE. 2020. Mammary gland (mamma, uber, mastos). In: König HE , Liebich GG, Veterinary Anatomy of Domestic Animals. Stuttgart, Germany: Georg Thieme Verlag KG. Pp. 642-648. ISBN: 978-3-13-242933-8 https://vetbooks.ir/veterinary-anatomy-of-domestic-animals-textbook-and-colour-atlas-7th-edition/

RODWELL WV. 2018. Catabolism of proteins and amino acid nitrogen. In: Rodwell WV, Bender AD, Botham MK, Kennelly JP , Weil AP, Harper’s Illustrated Biochemistry. United States: McGraw-Hill Education / Medical. Pp. 661-686. ISBN: 978-1-25-983793-7 https://accessmedicine.mhmedical.com/book.aspx?bookID=2386

ROWLAND AA, Voeltz GK. 2012. Endoplasmic reticulum-mitochondria contacts: function of the junction. Nature Reviews Molecular Cell. 13(10):607-625. ISSN: 1471-0080.

https://doi.org/10.1038/nrm3440

SAHEKI Y, De Camilli P. 2017. Endoplasmic Reticulum-Plasma Membrane Contact Sites. Annual Review of Biochemistry. 86:659-684. ISSN: 1545-4509.

https://doi.org/10.1146/annurev-biochem-061516-044932

SAIKIA D, Hassani MI, Walia A. 2022. Goat milk and its nutraceutical properties. International Journal of Applied Research. 8(4):119-122. ISSN: 2394-5869.

https://doi.org/10.22271/allresearch.2022.v8.i4b.9639

SAIPIN N, Thuwanut P, Thammacharoen S, Rungsiwiwut R. 2020. Effect of incubation temperature on lactogenic function of goat milk-derived mammary epithelial cells. In Vitro Cellular & Developmental Biology. 56(10):842-846. ISSN: 1543-706X.

https://doi.org/10.1007/s11626-020-00529-3

SANHUEZA J, Valenzuela R, Valenzuela A. 2012. Cholesterol metabolism: increasingly complex. Grasas y Aceites. 63(4):373-382. ISSN: 1988-4214.

https://doi.org/10.3989/gya.035512

SANSI MS, Iram D, Zanab S, Vij S, Puniya AK, Singh A, Ashutosh, Meena S. 2022. Antimicrobial bioactive peptides from goat Milk proteins: In silico prediction and analysis. Journal of Food Biochemistry. 45(10):e14311. ISSN: 1745-4514.

https://doi.org/10.1111/jfbc.14311

SEOANE A, Brea RJ, Fuertes A, Podolsky KA, Devaraj NK. 2018. Biomimetic generation and remodeling of phospholipid membranes by dynamic imine chemistry. Journal of the American Chemical Society. 140(27):8388-8391. ISSN: 1520-5126.

https://doi.org/10.1021/jacs.8b04557

SINGH A, Rajeev S. 2020. DNA: an important component of life. In: Torrens F, Mahapatra KD , Haghi AK, Biochemistry, Biophysics, and Molecular Chemistry: Applied Research and Interactions. Florida, United States: Apple Academic Press, Inc. Pp. 195-208. ISBN: 9781771888165. https://www.routledge.com/Biochemistry-Biophysics-and-Molecular-Chemistry-Applied-Research-and/Torrens-Mahapatra-Haghi/p/book/9781774635100

SONG Z, Xiaoli AM, Yang F. 2018. Regulation and metabolic significance of de novo lipogenesis in adipose tissues. Nutrients. 10(10):1-10. ISSN: 2072-6643.

https://doi.org/10.3390/nu10101383

STURLEY SL, Hussain MM. 2012. Lipid droplet formation on opposing sides of the endoplasmic reticulum. Journal of Lipid Research. 53(9):1800-1810. ISSN: 1539-7262. https://doi.org/10.1194/jlr.R028290

SUBURU J, Shi L, Wu J, Wang S, Samuel M, Thomas MJ, Kock ND, Yang G, Kridel S, Chen YQ. 2014. Fatty acid synthase is required for mammary gland development and milk production during lactation. American Journal of Physiology-Endocrinology and Metabolism. 306(10):E1132-E1143. ISSN: 1522-1555.

https://doi.org/10.1152/ajpendo.00514.2013

SVENNERSTEN SK, Olsson K. 2005. Endocrinology of milk production. Domestic Animal Endocrinology. 29(2):241-258. ISSN: 18790054.

https://doi.org/10.1016/j.domaniend.2005.03.006

SWAISGOOD HE. 2003. Protein composition of milk: identification, structure, and chemical composition. In: Fox PF , McSweeney PLH, Advanced dairy chemistry: proteins part A. Cork, Ireland: Springer Science. Pp. 140-225. ISBN: 9780306472718.

https://link.springer.com/book/10.1007/978-1-4419-8602-3

THUL TA, Corwin EJ, Carlson NS, Brennan PA, Young LJ. 2020. Oxytocin and postpartum depression: A systematic review. Psychoneuroendocrinology. 120(1):104-109. ISSN: 1873-3360. https://doi.org/10.1016/j.psyneuen.2020.104793

TORTORA JG, Funke RB, Case LC. 2019. Organic compounds. Structure and chemistry: carbohydrates, lipids, proteins, nucleic acids. In: Beauparlant S, Microbiology: An Introduction. New York, United States: Pearson. Pp. 33-47. ISBN: 978-0-13-460518-0. https://www.pearson.com/en-us/subject-catalog/p/microbiology-an-introduction/P200000006850/9780135789377

VERSCHUEREN KHG, Blanchet C, Felix J, Dansercoer A, De Vos D, Bloch Y, Van Beeumen J, Svergun D, Gutsche I, Savvides SN, Verstraete K. 2019. Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature. 568(7753):571-575. ISSN: 1476-4687. https://doi.org/10.1038/s41586-019-1095-5

VIDAL ME. 2013. Lácteos: oferta y demanda en el contexto regional y mundial. En 1º Foro de Agricultura de América del Sur. Oficina de Programación y Política Agropecuaria, (Ed.). Consejo Agropecuario del Sur. Foz de Iguazú, Brasil.

https://www.odepa.gob.cl/publicaciones/noticias/noticias-institucionales/primer-foro-de-la-agricultura-en-america-del-sur

WEIL AP. 2018a. Protein synthesis and the genetic code. In: Rodwell WV, Bender AD, Botham MK, Kennelly JP , Weil AP, Harper’s Illustrated Biochemistry. United States: McGraw-Hill Education / Medical. Pp. 955-991. ISBN: 978-1-25-983793-7.

https://accessmedicine.mhmedical.com/book.aspx?bookID=2386

WEIL AP. 2018b. RNA synthesis, processing and modification. In: Rodwell WV, Bender AD, Botham MK, Kennelly JP , Weil AP, Harper’s Illustrated Biochemistry. United States: McGraw-Hill Education / Medical. Pp. 911-954. ISBN: 978-1-25-983793-7. https://accessmedicine.mhmedical.com/book.aspx?bookID=2386

WILSON C, Venditti R, Rega LR, Colanzi A, D'Angelo G, De Matteis MA. 2011. The Golgi apparatus: an organelle with multiple complex functions. Biochemical Journal. 433(1):1-9. ISSN: 1470-8728. https://doi.org/10.1042/BJ20101058

ZHANG C, Liu P. 2019. The new face of the lipid droplet: lipid droplet proteins. Proteomics. 19(10):e1700223. ISSN: 1615-9861. https://doi.org/10.1002/pmic.201700223

Publicado

2023-05-20

Número

Sección

Revisiones de Literatura

Artículos más leídos del mismo autor/a